2,4,5-Trifluorobenzoic Acid And Derivatives
C7H3F3O2 CAS NO.446-17-3

2,4,5-Trifluorobenzoic acid is a white to light yellow crystal powder.
Application
One of the most common synthetic applications of 2,4,5-Trifluorobenzoic acid (TFBA )is as a precursor for the synthesis of various heterocyclic compounds. For example, TFBA can be used as a starting material for the synthesis of 2,4,5-trifluorobenzo[b]thiophene, a key intermediate in the production of OLED materials. It can also be used to prepare derivatives such as 2,4,5-trifluorobenzoic acid hydrazide, which exhibits antimicrobial activity against various microorganisms.
TFBA is also an important intermediate for the synthesis of biologically active compounds. For instance, it has been used as a building block for the synthesis of the potent antitumor agent Taxol (paclitaxel). In addition, TFBA derivatives have shown potential activity as anticancer agents, anti-inflammatory agents, and in the treatment of Alzheimer's disease.
Physical Properties
|
Melting point |
94-96 °C (lit.) |
|
Boiling point |
241.9±35.0 °C(Predicted) |
|
Assay |
≥99.0% |
|
Molecular mass |
176.09 |
|
Solubility |
Chloroform(slightly), DMSO(slightly) |
|
Package |
25kgs or according customer requirement |
|
If need more information like COA/MSDS etc,pls contact: sales01@huayangco.com |
|
Security Information
[Symbol]: GHS07
[Signal word]: Warning
[Hazard Statement]: H315-H319-H335
[Cautionary Statement]: P261-P305 + P351 + P338
[Personal Protective Equipment]: dust mask type N95 (US); Eyeshields; Gloves
[Hazard Code (Europe)]: Xi:Irritant
[Risk Statement (Europe)]: R36/37/38
[Safety Statement (Europe)]: S26-S36-S24/25
[Dangerous Goods Transport Code]: NONH for all modes of transport
[WGK Germany]: 3
[HS Code]: 2916399090
Description of necessary first aid measures
general advice
Show this safety data sheet to the doctor who attends the scene.
inhalation
If inhaled, move victim to fresh air. If breathing stops, perform artificial respiration.
skin contact
Rinse with soap and plenty of water.
eye contact
Flush thoroughly with plenty of water for at least 15 minutes and consult a doctor.
ingest
Never give anything by mouth to an unconscious person. Rinse mouth with water.




Packing, Storage, Handling and Transportation
2,4,5-Trifluorobenzoic Acid And Derivatives should be sealed in dry place at room temperature.

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