Fluorobenzaldehyde
Haoxing Kaibang New Material Technology Co., Ltd is a company integrating R & D, production, sales,professional Pharmaceutical Intermediates manufacturer, we specialize in the development and production of Active Pharmaceutical Intermediates (APIs) and Pharmaceutical Intermediates, and earned a reputations leading supplier of innovative, high quality chemicals. Shaoxing Kaibang New Material Technology Co., Ltd has a well-established research & kilo laboratory to serve our global customers in multi grams to kilograms level, and also conduct process development, has own production line, Pentafluorophenol, Difluorophenol, Tetrafluorobenzyl Alcohol etc as our main competitive products, highly purified,high quality, well appreciated by their purchasers.
Why Choose Us
Our Certifications
Kaibang takes immense pride in holding certifications from ISO 9001:2015, ISO 14001:2015, and ISO 45001:2018, a testament to our unwavering commitment to quality, efficiency, flexibility, and cost competitiveness.
Quality Control
Quality is our Culture and our Promise to our customers all over the world! From raw material purchasing to production progress, finish product testing and Packing, we insist to doing tracing and Quality control for each single step just to realize our promise!
24H Online Service
Beyond competence products, we also do 7 X 24 hours After Sales Service!We have a wide market for products of highpurity and quality, which are well received bypurchasers.
Fluorobenzaldehyde refers to a group of organic compounds characterized by a benzaldehyde molecule with one or more fluorine atoms attached. The most common form is 4-Fluorobenzaldehyde (also known as p-Fluorobenzaldehyde), which features a fluorine atom in the para (4-) position relative to the aldehyde group. It's often used as a building block in organic synthesis, particularly for creating pharmaceuticals, agrochemicals, and advanced materials.
Product Specification
We provide the following product specifications
|
Refractive index |
N20/D 1.482(lit.) |
|
Boiling point |
168 °C (lit.) |
|
Density |
1.408 g/mL at 25 °C (lit.) |
|
Molecular mass |
142.1 |
|
Assay |
≥98.0% |
|
Flash point |
137 °F |
|
Package |
25kgs or according customer requirement |
Common Types
We provide the following product introduce
≥98.0% 2,4,5-Trifluorobenzaldehyde
Utilizing 2,4,5-trifluorotoluene as the starting material, create 2,4,5-trifluorodichlorobenzyl by side chain chlorination with chlorine, and then hydrolyze to produce 2,4,5-trifluorobenzyl benzoaldehyde. 2,4,5-trifluorotoluene, the method's raw ingredient, is costly and hard to come by.It starts with 2,4,5-trifluorobenzene and combines with n-butyllithium at room temperature to produce 2,4,5-trifluorobenzaldehyde. DMF is then added. This method's reaction conditions are harsh, and the raw components are extremely pricey.
2,6-Difluorobenzaldehyde
2,6-Difluorobenzaldehyde is an aromatic aldehyde with two fluorine atoms attached to the meta positions of the benzene ring. This structural motif confers unique properties to 2,6-Difluorobenzaldehyde that make it a valuable building block for organic synthesis.
2,4,6-Trifluorobenzaldehyde
2,4,6-Trifluorobenzaldehyde, also known as 2,4,6-Tri-F-Benzaldehyde, is a versatile chemical compound that belongs to the family of benzaldehydes. Due to its unique properties, it is widely used as a key building block for various pharmaceutical and agrochemical intermediates.
2,4-Difluorotoluene Synthesis
Add concentrated hydrochloric acid (40 ml) to a 250 ml three-necked reaction flask covered with solid paraffin film. Cool to 0°C. Add 2,4-diaminotoluene (12.2 g, 0.1 mol) and stir to dissolve. Add 40% fluoboric acid (80 ml, 0.5 mol). Stir thoroughly. Add NaNO: (25 g, 0.36 mol) water (40 ml) solution dropwise. Keep the internal temperature below 0 cc. The addition should be finished in 1 to 2 hours. Continue stirring at a low temperature for 0.5 hours. Use potassium iodide-starch test paper to determine the end point. Sulfamic acid can be used to eliminate excess NaNO. Following suction filtering, the filter cake was cleaned using ether (50 ml×2), cold fluoroboric acid (50 ml), ethanol-water solution (1:1), v/v) (50 ml), and 95% ethanol solution (50 ml). Vacuum dry (no heat) after letting it dry.
The result was a white solid (18.4 g, 75.5%). The diazonium salt of bisfluoroborate (24.5g, 0.1mol) prepared above should be added to a 50ml round-bottomed flask in a fume hood. It should be connected to a distillation device and a BF gas absorption device. A small fire should be used initially, followed by a strong fire. The reaction bottle should be heated to break down the bisfluoroboric acid diazonium salt until all of the breakdown products have evaporated. A colorless liquid (5.5g, 42.5%) with a refractive index of 1.4486 and a content of 98.5% (GC) was obtained by extracting the distillate using methylene chloride, washing it with 10% NaOH solution (10ml×2) and water (20ml×2) in that order, drying it over calcium chloride, fractionating it under normal pressure, and collecting the products at 110 to 120°C.
Applications
Pharmaceuticals
It serves as an intermediate in the synthesis of drugs, including anti-inflammatory and analgesic compounds.
Organic Synthesis
It's a versatile building block for creating complex molecules in organic chemistry.
Material Science
It can be incorporated into polymers and resins to enhance their properties.
Agrochemicals
It plays a role in the development of pesticides and herbicides.
Precautions
Inhalation: Move victim to fresh air, keep breathing unobstructed, and rest. Call a poison center/doctor immediately.
Skin Contact: Remove/take off all contaminated clothing immediately. Wash gently with plenty of soap and water. Call a poison center/doctor immediately.
Eye Contact: Rinse carefully with water for several minutes. If convenient and easy to operate, remove contact lenses. Continue cleaning. Call a poison center/doctor immediately.
Ingestion: Call a poison center/physician immediately. gargle. Never induce vomiting.
Protection for emergency responders: Rescuers need to wear personal protective equipment, such as rubber gloves and air-tight goggles.
Certifications
Packing
We're professional fluorobenzaldehyde manufacturers and suppliers in China, specialized in providing high quality customized service. We warmly welcome you to buy fluorobenzaldehyde at low price from our factory. Contact us for quotation.
Nonafluoro 1 Butanesulfonyl Chloride CAS NO 2991 84 6, Index Name Not Yet Assigned CAS No 2179321 09 4, 2 6 Difluorobenzyl Alcohol 99 5