≥98.0% 2,4,6-Trifluorobenzaldehyde CAS No.: 58551-83-0
C7H₃F₃O
CAS No.: 58551-83-0

Application
2,4,6-Trifluorobenzaldehyde is an inhibitor of serine protease. It is a competitive inhibitor of the enzyme lp-pla2 that has been shown to be involved in the replication of DNA. The inhibitory effect has been proven by its ability to prevent the reaction solution from changing color when exposed to lp-pla2 in coordination chemistry studies. 2,4,6-Trifluorobenzaldehyde has also been shown to inhibit cancer cells and inflammatory compounds such as those found in autoimmune diseases.
In the first stage, diisopropylamine and n-butyllithium combine to form lithium diisopropylamine. Utilizing the potent ortho-positioning action of fluorine, this process is carried out at the 2-position of 1,3,5-trifluorobenzene. Lithium salt 1 is the result of the hydrogen grabbing process.
The intermediate lithium salt is produced in the reaction step by the reaction of lithium diisopropylamine with 1,3,5-trifluorobenzene. This crucial stage in the synthesis process establishes the course and end result of the next reaction.
In order to acquire the crude product, the aldehyde group is formed and purified in the subsequent reaction by varying the pH and adding various reagents.
To guarantee the finished product's quality and purity, purification stages entail additional processing of the raw material.
Physical Properties
|
Melting point |
60 °C |
|
Boiling point |
165℃ |
|
Density |
1.407 |
|
Molecular mass |
160.09 |
|
Assay |
≥98.0% |
|
Flash point |
46.6±17.4 ℃ |
|
Package |
50kgs or according customer requirement |
|
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|
Physical and chemical properties
[Density]: 1.4±0.1 g/cm³
[Boiling point]: 164.6±35.0 ℃ at 760 mmHg
[Melting point]: 60 ℃
[Molecular formula]: C7H₃F₃O
[Molecular weight]: 160.093
[Flash point]: 46.6±17.4 ℃
[Exact Mass]: 160.013596
[PSA]: 17.07000
[LogP]: 1.92
[Appearance]: White flakes
[Vapor pressure]: 2.0±0.3 mmHg at 25℃
[Refractive Index]: 1.492
[ Storage conditions ]:
Store in an airtight container in a dry, cool place
[Stability]:
Avoid contact with oxides
Security Information
[Symbol]: GHS07
[Signal word]: Warning
[Hazard Statement]: H315-H319
[Cautionary Statement]: P305 + P351 + P338
[Hazard Code (Europe)]: Xn:Harmful;
[Risk Statement (Europe)]: R22; R36/37/38
[Safety Statement (Europe)]: S26-S36-S37/39
[Dangerous Goods Transport Code]: NONH for all modes of transport
[HS Code]: 2913000090




Packing, Storage, Handling and Transportation
Nonafluorobutanesulfonyl fluoride should be kept in dark place, sealed in dry and stored in freezer under -20℃

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