≥99.0% 2,4,5-Trifluorobenzyl bromide CAS NO.157911-56-3

C₇H₄BrF₃

CAS NO.157911-56-3

product-716-760

Application

Discussing:
Reaction time and the ratio of raw materials
Analyze how time and the ratio of reaction raw materials affect the yield of 2,4,5-trifluorobenzyl bromide synthesis. The reaction yield is low and byproducts are formed when the ratio of 1,2,4-trifluorobenzene to paraformaldehyde is high. The ideal ratio is m(C6H3F3):m(paraformaldehyde)=1.0:0.875~0.865; the ideal reaction duration is 10 hours, and the production volume is high. The reaction is incomplete if it takes fewer than 10 hours, and more byproducts will be created if it takes more than 10 hours.
temperature of reaction
The impact of reaction temperature on 2,4,5-trifluorobenzyl bromide synthesis yield was examined. High reaction yield and satisfactory product purity were achievable at a reaction temperature of 40°C. The ideal reaction temperature is 40°C since too low a temperature results in low reaction activity and too high a temperature increases the likelihood of side reactions.

Physical Properties

Boiling point	188.8±35.0℃(Predicted)
Assay	≥99.0%
Molecular mass	225.01
Flash point	75.4±21.8 °C
Vapor pressure (mmHg)	0.8±0.3 mmHg at 25°C
LogP	3.09
Index of refraction	1.503
Package	50kgs or according customer requirement
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1. High reactivity: TFB has strong electrophilic properties that make it highly reactive towards nucleophilic agents. This reactivity makes it useful in a broad range of reactions, including nucleophilic substitutions, Grignard reactions, and cross-coupling reactions.

2. Selectivity: TFB's high reactivity makes it useful in reactions that require high selectivity. Chemical reactions that use TFB can produce highly selective products, which saves time and money compared to other synthetic routes.

3. Fluorinated compounds: Fluorinated compounds are known for their useful properties such as increased lipophilicity, bioavailability and metabolic stability. TFB can be used as an important building block for the synthesis of various bioactive and medicinally relevant fluorinated compounds.

4. Stability: TFB is a stable compound and can be stored for prolonged periods without significant decomposition. This stability makes it highly suitable for use in large-scale chemical processes.

5. Environment-friendly: TFB is an environment-friendly solution as it is easily recyclable and non-toxic. This makes it an ideal alternative to traditional toxic and hazardous reagents used in chemical reactions.

product-1200-956