Dimethyl Fluoromalonate

Dimethyl fluoromalonate is a chemical compound that belongs to the family of fluorinated organic compounds. It is a clear, colorless liquid with a fruity odor and a boiling point of 115-116 °C. The molecular formula for dimethyl fluoromalonate is C5H7FO4 and its molecular weight is 146.10 g/mol.

Dimethyl fluoromalonate

C₅H₇FO₄

CAS NO.344-14-9

Dimethyl fluoromalonate CAS No344-14-9

Application

Dimethyl fluoromalonate is a chemical compound that belongs to the family of fluorinated organic compounds. It is a clear, colorless liquid with a fruity odor and a boiling point of 111-112 °C. The molecular formula for dimethyl fluoromalonate is C₅H₇FO₄ and its molecular weight is 150.11 g/mol.

This chemical compound is mainly used in the pharmaceutical industry as a building block for the synthesis of a variety of drugs, including anticancer agents and antiviral drugs. It is also used as a reagent in organic synthesis for the preparation of various fluorinated compounds.

The synthesis of dimethyl fluoromalonate involves the reaction between malonic acid and hydrogen fluoride in the presence of a catalyst such as sulfuric acid. The reaction yields dimethyl fluoromalonate and water as byproducts.

Dimethyl fluoromalonate is a highly reactive molecule due to the presence of the fluorine atom. It can undergo various reactions such as nucleophilic substitution, esterification, and Michael addition. Its high reactivity also makes it a potent source of fluorine in organic synthesis.

Although dimethyl fluoromalonate is a useful building block in the pharmaceutical industry and organic synthesis, it must be handled with care due to its toxic and corrosive nature. It is important to follow proper safety protocols when handling this chemical compound.

Dimethyl fluoromalonate is an important chemical compound that finds its application in the synthesis of various drugs and organic compounds. Its reactivity and high potency make it a valuable building block in the pharmaceutical industry.

Physical Properties

Boiling point	111-112 °C(under press:45 Torr)
Assay	≥98.0%
Molecular mass	150.11
Flash point	38.4±16.7 ℃
Refractive index	1.4032
Package	25kgs or according customer requirement
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