2,5-Difluorophenol

C₆H₄F₂O

CAS No.:2713-31-7

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Application

There are several applications of 2,5-Difluorophenol, including:

1.The starting material, p-difluorobenzene, is subjected to two-step processes of LDA hydrogen extraction and hydrolysis: Simple operation, mild reaction conditions, easy-to-obtain raw ingredients, little side reactions, and industrial production suitability characterize this process. The yield is 84.5% overall.

2.Reaction of sulfuryl fluoride gas with 3,5-difluorophenol: At room temperature, combine 3,5-difluorophenol, triethylamine, and 1,4-dioxane. Then, slowly bubble through a sulfuryl fluoride balloon. It introduces sulfuryl fluoride gas. To acquire the desired product, acidify and extract using strong hydrochloric acid after a 24-hour reaction. Then, purify using silica gel column chromatography.‌

Physical Properties

MF	C₆H₄F₂O
Boiling point	157.1±20.0 °C at 760 mmHg
Density	1.4±0.1 g/cm3
Appearance	White crystal
Molecular mass	130.09
Assay	≥99%
Package	50kgs or according customer requirement
If need more information like COA/MSDS etc,pls contact: sales01@huayangco.com

Chemical Safety

product-160-110

GHS Hazard Statements

H228 (100%)	Flammable solid [Danger Flammable solids]
H302 (100%)	Harmful if swallowed [Warning Acute toxicity, oral]
H312 (100%)	Harmful in contact with skin [Warning Acute toxicity, dermal]
H315 (91.49%)	Causes skin irritation [Warning Skin corrosion/irritation]
H319 (91.49%)	Causes serious eye irritation [Warning Serious eye damage/eye irritation]
H332 (91.49%)	Harmful if inhaled [Warning Acute toxicity, inhalation]
H335 (100%)	May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

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