3-Fluorophenol

C₆H₅FO

CAS NO.372-20-3

product-715-756

3-Fluorophenol is an organic compound having a chemical formula of C6H5FO. It is an aromatic compound with a fluorine substituent on the ring. This compound is an important industrial chemical, and it is used mainly in the production of other chemicals like pharmaceuticals, agrochemicals, and dyes.

Synthesis of 3-Fluorophenol:

3-Fluorophenol can be made by several methods: one is the direct fluorination of phenol with hydrogen fluoride and antimony trioxide. Another method is through the nitration of fluorobenzene followed by SnCl2 reduction and hydrolysis.

Application

1. Pharmaceuticals

3-Fluorophenol is one of the key intermediates in the production of several pharmaceuticals like fenticonazole, an antifungal agent that is used to treat skin infections. It is also used in the development of other drugs like Toll-like Receptor 9 (TLR9) agonists.

2. Agrochemicals

Many agrochemicals like herbicides and insecticides use 3-Fluorophenol as an intermediate. It is also used in the production of abamectin used as a pesticide.

3. Dyes

3-Fluorophenol is used as an intermediate in the production of dyes like ethyl violet, which finds applications in the textile industry.

3-Fluorophenol is a vital compound in the chemical industry with widespread use as an intermediate in the synthesis of various pharmaceuticals, agrochemicals, and dyes.

Physical Properties

Melting point	8-12 ℃ (lit.)
Boiling point	178 ℃ (lit.)
Density	1.238 g/mL at 25 ℃ (lit.)
Molecular mass	112.1
Assay	≥99.0%
Flash point	160℉
Vapor pressure (mmHg)	0.7±0.3 mmHg at 25℃
LogP	1.93
Index of refraction	1.523
Water solubility	insoluble
Package	50kgs or according customer requirement
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