2,4-Difluorobenzyl Alcohol 56456-47-4

2,4-Difluorobenzyl Alcohol ,

C₇H₆F₂O CAS NO.56456-47-4

Synthesis via 2,4-difluorobenzonitrile‌:

‌Reduction reaction‌: Add pure water, glucose, NADP+, isopropanol and 2,4-difluorobenzonitrile to the reaction system, adjust the pH value, add liquid nitrile reductase and GDH, and react in a 30°C water bath for 20 hours, the conversion rate is 70%‌.
Each of these methods has advantages and disadvantages, and choosing the appropriate method depends on specific experimental conditions and needs. For example, although the synthesis method of 2,4-difluorobenzoic acid has many steps, the raw materials are easily available and the operation is safe; while the synthesis method of 2,4-difluorobenzonitrile has a higher conversion rate, but Specific enzymes and equipment are required.

MSDS

2,4-Difluorobenzyl alcohol

1. Chemicals

Product name: 2,4-Difluorobenzyl Alcohol

2. Hazard overview

GHS classification

Physical hazards

Flammable Liquid Class 4

Health hazards

Skin Corrosion/Irritation Level 2

Serious damage/irritation to eyes Category 2A

Environmental hazards not classified

GHS tag elements

icon or hazard symbol

signal word warning

Hazard Description Flammable Liquid

Cause skin irritation

Causes severe eye irritation

Precautionary statements

[Prevention] Keep away from open flames/hot surfaces.

Wash hands thoroughly after handling.

Wear protective gloves/goggles/mask.

[First aid measures] Eye contact: Rinse carefully with water for several minutes. If convenient and easy to operate, remove contact lenses. Continue rinsing.

Eye Contact: Get medical advice/attention

Skin Contact: Wash gently with plenty of soap and water.

If skin irritation: Get medical advice/attention.

Take off contaminated clothing and wash before reuse.

[Storage] Store in a well-ventilated place. Stay cool.

[Disposal] Hand over items/containers to industrial waste disposal facilities in accordance with local government regulations.

2,4-Difluorobenzyl alcohol

3. First aid measures

Inhalation: Move victim to fresh air, keep breathing unobstructed, and rest. If you feel unwell seek medical advice/attention.

Skin Contact: Remove/take off all contaminated clothing immediately. Wash gently with plenty of soap and water.

If skin irritation or rash occurs: Get medical advice/attention.

Eye Contact: Rinse carefully with water for several minutes. If convenient and easy to operate, remove contact lenses. Continue cleaning.

If eye irritation: Get medical advice/attention.

Ingestion: If you feel unwell, seek medical advice/attention. gargle.

Protection for emergency responders: Rescuers need to wear personal protective equipment, such as rubber gloves and air-tight goggles.

4. Firefighting measures

Suitable extinguishing media: dry powder, foam, water mist, carbon dioxide

Unsuitable extinguishing media: water stick

Special hazards: Be careful, it may decompose when burned or exposed to high temperatures to produce toxic fumes.

Specific methods: Fight the fire from upwind, and choose the appropriate fire-fighting method according to the surrounding environment.

Non-related personnel should evacuate to a safe place.

If fire is around: Remove removable containers if safe to do so.

Special protective equipment for firefighters: When fighting a fire, always wear personal protective equipment.

5. Accidental leakage measures

Personal protective measures, protective equipment, use personal protective equipment. Stay away from spills/leaks and stay upwind. Ensure adequate ventilation.

Emergency measures: The leakage area should be enclosed with safety belts, etc. to control the entry of non-related personnel.

Environmental measures: Prevent entry into sewers.

Methods and materials for containment and cleaning: Absorb the spill with suitable absorbent (e.g. old cloth, dry sand, soil, sawdust). Once there is a large leakage, build embankments to control it

system. Attachments or collections should be disposed of immediately in accordance with appropriate laws and regulations.

Secondary Hazardous Precautions Remove all sources of ignition. Fire extinguishers should be prepared in case of fire. Use spark-proof tools and explosion-proof equipment.

6. Handling and Storage

deal with

Technical measures: Handle in a well-ventilated area. Wear appropriate protective equipment. Prevent smoke generation. Keep away from open flames and hot surfaces.

Take steps to prevent the build-up of static electricity. Use explosion-proof equipment. Wash hands and face thoroughly after handling.

Precautions: Use closed system and ventilate.

Handling Precautions: Avoid contact with skin, eyes and clothing.

storage

Storage conditions: Keep container tightly closed. Store in a cool, dark, well-ventilated place.

Store away from incompatible materials such as oxidizers.

Packaging materials: as per law.

7. Exposure controls and personal protection

Engineering control: Install a closed system or local exhaust system as much as possible, and operators must not come into direct contact. Install shower and washing machine at the same time

Eye device.

personal protective equipment

Respiratory protection: gas mask. Subject to local and government regulations.

Hand protection: Protective gloves.

2,4-Difluorobenzyl alcohol

8. Exposure controls and personal protection

Eye protection: safety glasses. Wear a mask if the situation requires it.

SKIN AND BODY PROTECTION: Protective clothing. Wear protective boots if the situation requires it.

Packing, Storage, Handling and Transportation

2,4-Difluorobenzyl alcohol should be sealed in dry place at room temperature.

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