≥98.0% 2-Fluoro-acrylic Acid Methyl Ester

≥98.0% 2-Fluoro-acrylic acid methyl ester

C₄H₅FO₂

CAS No.: 2343-89-7

Add 300 ml of n-pentane, 31.5 g (1.05 mol) paraformaldehyde, 1.0 g p-phenol (Claisen), and 200.1 g (1 mol, theoretical yield) of the concentrated dry product of the prior process to a 1000 ml three-necked flask. 0.5% of sodium salt mass), maintain the temperature between 25 and 30°C, and halt the reaction after ten hours. To destroy the reaction solution, add 300 ml of water, mix for half an hour, and then separate the liquids. Following a neutralizing water wash, the organic phase is added under normal pressure (30–36°C) to eliminate n-pentane, and subsequently under reduced pressure (30–40°C). getting 47.5g of colorless liquid 2-fluorine original, P=-O.6MPa~-O.7MPa), yield: 42.4% (GC major content=97.5577%),1H-NMR ( 400 MHz,DMSO,TMS ) :δ ( ppm ) 5.41 ( m,2H ),3.79 ( s ,3H ) .IR ( KBr,pellet,cm-1) : 2947,2927,2869,1610,1552,1494,1456,1392,1298,1255,1186,1109,1066,1041 ,923,883,843,796.GC-MS m/z ( rel.int. ) : calcd 104.5,found 104.6.

Packing, Storage, Handling and Transportation

3-Fluorophenol should be kept in dark place under inert atmosphere at room temperature.

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