≥99.0% 1,2,4,5-Tetrafluorobenzene CAS No.: 327-54-8

≥99.0% 1,2,4,5-Tetrafluorobenzene CAS No.: 327-54-8

C₆H₂F₄

CAS No.: 327-54-8

Method of preparation
The primary techniques for synthesizing 1,2,4,5-tetrafluorobenzene are:

1. Perfluorocyclohexane was utilized as the starting material and created via an elimination reaction with zirconocene metal catalyst ((Cp2ZrCl2+Mg/HgCl2) Route to 1,2,4,5-tetrafluorobenzene), according to J.Am.Chem.Soc., Vol.118, No.7,
1996.

This process uses a precious metal catalyst, rare raw materials, and a 35% yield.

2. Hexafluorobenzene or pentafluorobenzene was utilized as a raw material to remove fluorine in the presence of reagents containing phosphorus to generate 1,2,4,5- Tetrafluorobenzene method, according to J.Am.Chem.Soc., 2014, 136, 4634–
4639.

Although this process yields roughly 98% of the sample, the catalyst preparation is challenging and the raw components are costly.

3. Hexafluorobenzene or pentafluorobenzene was utilized as the raw material, and fluorine was eliminated using a catalyst containing rhodium to create 1,2,4,5-tetrafluorobenzene, according to J. Fluorine Chem., 155 (2013), 132-142.

This process produces a lot of byproducts, has a low yield, and is challenging to create the catalyst that contains rhodium.
 

Packing, Storage, Handling and Transportation

Hexafluorobenzene should be sealed in dry place at room temperature.

Hot Tags: ≥99.0% 1,2,4,5-tetrafluorobenzene cas no.: 327-54-8, China ≥99.0% 1,2,4,5-tetrafluorobenzene cas no.: 327-54-8 manufacturers, suppliers, factory, Hexafluorobenzene C6F6 CAS NO 392 56 3, 1 3 5 Trifluorobenzene Benzene, , ,