2,4,5-Trifluorophenylacetic Acid

C₈H₅F₃O₂ CAS NO.209995-38-0

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2,4,5-Trifluorophenylacetic Acid: A Versatile Compound with Multiple Applications

Application

2,4,5-Trifluorophenylacetic acid is a white crystalline powder that has a range of applications in different fields. It is a derivative of phenylacetic acid, and its unique properties make it a popular compound in pharmaceuticals, agrochemicals, and material sciences.

2,4,5-trifluorophenyl acetic acid preparation In batches, add 10g x 3 solid dry ice under nitrogen protection to the reaction solution that contains 61g of the 2,4,5-trifluorobenzylmagnesium chloride that was produced in Example 1. Adjust the reaction temperature between 0°C and 15°C and add it every three hours. Once all of the dry ice has been added, adjust the temperature to between 0°C and 28°C and let it react for three to four hours. Next, gradually add the reaction solution dropwise to the ice-water mixture's 2mol/LHCl solution. Combine the organic layers and use 30g × 3 ethyl acetate to extract the aqueous phase from the Chemicalbook. 54g of crude 2,4,5-trifluorophenylacetic acid can be obtained by washing 40g×2 with saturated brine, drying the organic phase with anhydrous sodium sulfate, filtering, and then evaporating the filtered liquid until it is completely dry. 50.7g of 2,4,5-trifluorophenylacetic acid was obtained by recrystallizing the crude product of 2,4,5-trifluorophenylacetic acid with 140 mL of anhydrous methanol.

Physical Properties

Melting point	121-125℃
Boiling point	255.0±35.0 ℃(Predicted)
Assay	≥99.0%
Molecular mass	190.12
Solubility	Chloroform(slightly), DMSO(slightly), Methanol(slightly)
Package	25kgs or according customer requirement
If need more information like COA/MSDS etc,pls contact: sales01@huayangco.com

Physical and chemical properties

[Density]: 1.5±0.1 g/cm³

[Boiling point]: 255.0±35.0 ℃ at 760 mmHg

[Melting point]: 121-125℃

[Molecular formula]: C8H5F₃O₂

[Molecular weight]: 190.119

[Flash point]: 108.0±25.9 ℃

[Exact Mass]: 190.024170

[PSA]: 37.30000

[LogP]: 1.67

[Vapor pressure]: 0.0±0.5 mmHg at 25℃

[Refractive Index]: 1.489

[ Storage conditions ]:

Storage method: airtight, cool, ventilated and dry place

[Stability]:

Avoid oxides

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Packing, Storage, Handling and Transportation

2,4,5-Trifluorophenylacetic acid should be sealed in dry place at room temperature.

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FAQ

Q: Do you have custom package service?

A: Yes. Please send us the requirement, we will make the exact same package basing on your require.

Q: Are you a manufacturer or a trading company?

A: We are a manufacturer.

Q: What is the universal lead-time for order delivery?

A: Small production: 15-20 days ,Mass production :30-40 days or basing on your qty.

Q: What payment terms do you accept?

A: T/T, we also accept most other convenient methods of payment.

Q: When can I get the feedback after we sent the enquiry?

A: We will reply you within 12 hours in working day.

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